When a stock exchange closes, the stocks of companies and indices listed on that exchange become unavailable for trading.
Stock exchange time schedule:
12/24/2015 – 12/26/2015 – Exchanges in many countries are closed or operate on a shortened day (Christmas)
12/28/2015 – Stock exchanges in Australia, United Kingdom, Canada, and New Zealand are closed (national holidays)
12/30/2015 – Short day on the Japanese stock exchanges (national holiday)
12/31/2015 – 01/01/2016 – Most of the world stock exchanges are closed (New Year’s Day)
12/31/2015 – 01/12/2016 – Moscow Stock Exchange is closed (New Year’s Day)
OTC
OTC mode is available all the time, when stock exchanges around the world are closed!